Thursday, April 10, 2014

CALCIUM STONE: WHAT ARE THE CAUSES?

Most calcium stones are composed of calcium oxalate (a lesser number are of calcium phosphate) and 80 to 90% are idiopathic (no discoverable cause). Some are associated with increased oxalate secretion and 10 to 15% are associated with hypercalciuria. Hypercalciuria may be associated with hyper- calcaemia particularly those associated with primary hyperparathyroidism, or normocalcaemia (normocalcaemic hypercalciuria) -- idiopathic or associated with: renal tubular acidosis, carbonic anhydrase inhibitors, immobilisation, hyper- thyroidism, Paget's disease, medullary sponge kidney.
Depending on the cause hypercalciuria may be: absorptive due to increased intestinal calcium absorption,
renal due to decreased tubular calcium reabsorption,
with secondary enhanced intestinal absorption of calcium resorptive, due to increased mobilization of skeletal (bone) calcium Triple phosphate stones.

posted from Bloggeroid

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